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Model List of Essential Medicines
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Found 25 recommendations for 18 medicines and 8 therapeutic equivalents
Removed recommendations and rejected applications are shown.
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8.2.2. Targeted therapies
Abemaciclib
General information
Section
Targeted therapies
Indications
Therapeutic equivalent to
palbociclib
for
Other specified malignant neoplasms of breast
Afatinib
General information
Section
Targeted therapies
Indications
Therapeutic equivalent to
erlotinib
for
Other specified malignant neoplasms of bronchus or lung
All-trans retinoic acid
General information
Section
Targeted therapies
Oral > Solid: 10 mg capsule
Indications
Acute myeloid leukaemia with recurrent genetic abnormalities
Binimetinib
General information
Section
Targeted therapies
Indications
Therapeutic equivalent to
trametinib
for
Other specified melanoma of skin
Bortezomib
General information
Section
Targeted therapies
Parenteral > General injections > unspecified: 3.5 mg in vial powder for injection
Indications
Plasma cell myeloma
Cobimetinib
General information
Section
Targeted therapies
Indications
Therapeutic equivalent to
trametinib
for
Other specified melanoma of skin
Crizotinib
General information
Section
Targeted therapies
Oral > Solid: 200 mg; 250 mg
Oral > Solid > capsule: 200 mg; 250 mg
Indications
Other specified malignant neoplasms of bronchus or lung
Anaplastic large cell lymphoma, ALK-positive
Dabrafenib
General information
Section
Targeted therapies
Oral > Solid: 50 mg; 75 mg
Indications
Other specified melanoma of skin
Dasatinib
General information
Section
Targeted therapies
Oral > Solid: 20 mg tablet; 50 mg tablet; 70 mg tablet; 80 mg tablet; 100 mg tablet; 140 mg tablet
Indications
Chronic myeloid leukaemia, not elsewhere classified
Encorafenib
General information
Section
Targeted therapies
Indications
Therapeutic equivalent to
dabrafenib
for
Other specified melanoma of skin
Erlotinib
General information
Section
Targeted therapies
Oral > Solid: 100 mg; 150 mg
Indications
Other specified malignant neoplasms of bronchus or lung
Everolimus
General information
Section
Targeted therapies
Oral > Solid > dispersible tablet: 2 mg; 3 mg; 5 mg
Oral > Solid > tablet: 2.5 mg; 5 mg; 7.5 mg; 10 mg
Indications
Other specified gliomas of brain
Gefitinib
General information
Section
Targeted therapies
Indications
Therapeutic equivalent to
erlotinib
for
Other specified malignant neoplasms of bronchus or lung
Ibrutinib
General information
Section
Targeted therapies
Oral > Solid: 140 mg
Indications
Chronic lymphocytic leukaemia or small lymphocytic lymphoma
Imatinib
General information
Section
Targeted therapies
Oral > Solid: 100 mg; 400 mg
Indications
B lymphoblastic leukaemia or lymphoma with t(9:22) (q34;q11.2); BCR-ABL1
Gastrointestinal stromal tumour of unspecified gastrointestinal sites
Chronic myeloid leukaemia, not elsewhere classified
Nilotinib
General information
Section
Targeted therapies
Oral > Solid > capsule: 150 mg; 200 mg
Indications
Chronic myeloid leukaemia, not elsewhere classified
Osimertinib
General information
Section
Targeted therapies
Oral > Solid: 40 mg (as mesylate); 80 mg (as mesylate)
Indications
Other specified malignant neoplasms of bronchus or lung
Palbociclib
General information
Section
Targeted therapies
Oral > Solid: 75 mg; 100 mg; 125 mg
Indications
Other specified malignant neoplasms of breast
Pertuzumab
General information
Section
Targeted therapies
Parenteral > General injections > IV: 240 mg per 14 mL in vial concentrated solution
Indications
Carcinoma of breast, specialised type
Ribociclib
General information
Section
Targeted therapies
Indications
Therapeutic equivalent to
palbociclib
for
Other specified malignant neoplasms of breast
Rituximab
General information
Section
Targeted therapies
Parenteral > General injections > IV: 100 mg per 10 mL in 10 mL vial; 500 mg per 50 mL in 50 mL vial
Indications
Follicular lymphoma
Chronic lymphocytic leukaemia or small lymphocytic lymphoma
Diffuse large B-cell lymphomas
Burkitt lymphoma including Burkitt leukaemia
Trametinib
General information
Section
Targeted therapies
Oral > Solid: 0.5 mg; 2 mg
Indications
Other specified melanoma of skin
Trastuzumab
General information
Section
Targeted therapies
Parenteral > General injections > IV: 60 mg in vial powder for injection; 150 mg in vial powder for injection; 440 mg in vial powder for injection
Indications
Carcinoma of breast, specialised type
Trastuzumab emtansine
General information
Section
Targeted therapies
Parenteral > General injections > IV: 100 mg in vial powder for injection; 160 mg in vial powder for injection
Indications
Carcinoma of breast, specialised type
Vemurafenib
General information
Section
Targeted therapies
Indications
Therapeutic equivalent to
dabrafenib
for
Other specified melanoma of skin
Zanubrutinib
General information
Section
Targeted therapies
Oral > Solid: 80 mg
Indications
Mantle cell lymphoma
Chronic lymphocytic leukaemia or small lymphocytic lymphoma