General description
Dexamethasone is a corticosteroid used in the treatment of various conditions where corticosteroids are indicated, including pain and oedema due to malignancy, nausea and vomiting, and in treatment protocols for some blood tissue cancers.
INN
Dexamethasone
Medicine type
Chemical agent
EML status history
First added in 1977
(TRS
615)
for
Lymphoid leukaemia, not elsewhere classified
Added in 1984
(TRS
722)
for
Allergic or hypersensitivity conditions of unspecified type
Added in 1991
(TRS
825)
for
Palliative care
Added in 2009
(TRS
958)
for
Nausea or vomiting
Added in 2013
(TRS
985)
for
Respiratory distress syndrome of the newborn, altered by maternal corticosteroid therapy
Added in 2019
(TRS
1021)
for
Plasma cell myeloma
Added in 2021
(TRS
1035)
for
Burkitt lymphoma including Burkitt leukaemia
Added in 2023
(TRS
1049)
for
Anaplastic large cell lymphoma, ALK-negative
Added in 2023
(TRS
1049)
for
Anaplastic large cell lymphoma, ALK-positive
Wikipedia
DrugBank
Recommendations
Section
Hormones and antihormones
- Oral > Liquid: 2 mg per 5 mL (as sodium phosphate)
- Parenteral > General injections > unspecified: 4 mg per mL in 1 mL ampoule dexamethasone phosphate (as sodium phosphate, equivalent to 3.3 mg/mL dexamethasone base)
- Oral > Solid > tablet: 2 mg (as dexamethasone base); 4 mg (as dexamethasone base)
- Parenteral > General injections > unspecified: 4 mg per mL in 1 mL ampoule dexamethasone phosphate (as sodium phosphate, equivalent to 3.3 mg/mL dexamethasone base
- Oral > Solid > tablet: 4 mg (as dexamethasone base)
- Oral > Liquid: 2 mg per 5 mL
- Oral > Solid: 2 mg; 4 mg
- Parenteral > General injections > unspecified: 4 mg per mL in 1 mL ampoule (as disodium phosophate salt)
Section
Antiallergics and medicines used in anaphylaxis
- Oral > Liquid: 0.5 mg per 5 mL (as sodium phosphate); 2 mg per 5 mL (as sodium phosphate)
- Parenteral > General injections > unspecified: 4 mg per mL in 1 mL ampoule dexamethasone phosphate (as sodium phosphate, equivalent to 3.3 mg/mL dexamethasone base)
- Oral > Solid > tablet: 0.5 mg (as dexamethasone base); 0.75 mg (as dexamethasone base); 1.5 mg (as dexamethasone base); 2 mg (as dexamethasone base); 4 mg (as dexamethasone base)
Section
Antiemetic medicines
- Oral > Liquid: 0.5 mg per 5 mL (as sodium phosphate); 2 mg per 5 mL (as sodium phosphate)
- Parenteral > General injections > unspecified: 4 mg per mL in 1 mL ampoule dexamethasone phosphate (as sodium phosphate, equivalent to 3.3 mg/mL dexamethasone base)
- Oral > Solid > tablet: 0.5 mg (as dexamethasone base); 0.75 mg (as dexamethasone base); 1.5 mg (as dexamethasone base); 4 mg (as dexamethasone base); 2 mg (as dexamethasone base)
Indications
Section
Other medicines administered to the mother
- Parenteral > General injections > unspecified: 4 mg per mL (dexamethasone phosphate (as sodium))
Section
Medicines for other common symptoms in palliative care
- Oral > Liquid: 2 mg per 5 mL (as sodium phosphate); 0.5 mg per 5 mL (as sodium phosphate)
- Parenteral > General injections > unspecified: 4 mg per mL in 1 mL ampoule (dexamethasone phosphate (as sodium phosphate) equialent to 3.3 mg dexamethasone base)
- Oral > Solid > tablet: 2 mg (as dexamethasone base); 4 mg (as dexamethasone base); 0.5 mg (as dexamethasone base); 0.75 mg (as dexamethasone base); 1.5 mg (as dexamethasone base)
Indications