General description
Amoxicillin is an extended spectrum penicillin antibiotic. Clavulanic acid is a beta-lactamase inhibitor.
INN
Amoxicillin + clavulanic acid
ATC codes
Medicine type
Chemical agent
Antibiotic groups
EML status history
First added in 1997
(TRS
882)
for
Bacterial infection of unspecified site
Added in 2017
(TRS
1006)
for
Acute otitis media
Added in 2017
(TRS
1006)
for
Infectious cystitis
Added in 2017
(TRS
1006)
for
Chronic obstructive pulmonary disease with acute exacerbation
Added in 2017
(TRS
1006)
for
Acute sinusitis
Added in 2017
(TRS
1006)
for
Bacterial cellulitis, erysipelas or lymphangitis
Added in 2017
(TRS
1006)
for
Osteomyelitis or osteitis
Added in 2017
(TRS
1006)
for
Bacterial infection of joint
Removed in 2017
(TRS
1006)
for
Bacterial infection of unspecified site
Added in 2017
(TRS
1006)
for
Neutropenia
Added in 2017
(TRS
1006)
for
Peritoneal abscess
Added in 2017
(TRS
1006)
for
Peritonitis
Added in 2017
(TRS
1006)
for
Bacterial pneumonia
Added in 2017
(TRS
1006)
for
Other specified pneumonia
Added in 2019
(TRS
1021)
for
Other specified prophylactic measures
Added in 2019
(TRS
1021)
for
Multi-drug resistant Mycobacterium tuberculosis
Wikipedia
DrugBank
Recommendations
Section
Access group antibiotics
- Parenteral > General injections > IV: 500 mg (as sodium salt) + 100 mg (as potassium salt) powder for injection; 1000 mg (as sodium salt) + 200 mg (as potassium salt) powder for injection
- Oral > Solid > tablet: 500 mg (as trihydrate) + 125 mg (as potassium salt)
- Oral > Liquid: 125 mg (as trihydrate) + 31.25 mg (as potassium salt) / 5 mL powder for oral liquid; 250 mg (as trihydrate) + 62.5 mg (as potassium salt) / 5 mL powder for oral liquid
- Oral > Solid > dispersible tablet: 200 mg (as trihydrate) + 28.5 mg (as potassium salt); 250 mg (as trihydrate) + 62.5 mg (as potassium salt)
- Oral > Solid > tablet: 500 mg (as trihydrate) + 125 mg (as potassium salt); 875 mg (as trihydrate) + 125 mg (as potassium salt)
Indications
First choice
Peritonitis (mild-moderate) Bacterial pneumonia (Community-acquired pneumonia - severe) [children] Other specified pneumonia (Hospital-acquired pneumonia) Peritoneal abscess (mild-moderate) Neutropenia (low-risk) Infectious cystitis Acute sinusitis Bacterial cellulitis, erysipelas or lymphangitis Chronic obstructive pulmonary disease with acute exacerbation
Other indications
Section
Antituberculosis medicines
- Oral > Liquid: 250 mg (as trihydrate) + 62.5 mg (as potassium salt) / 5 mL powder for oral liquid
- Oral > Solid > tablet: 500 mg (as trihydrate) + 125 mg (as potassium salt)
Indications