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Fexinidazole
Essential medicine status
Section:
6. Anti-infective medicines 6.5. Antiprotozoal medicines 6.5.5. Antitrypanosomal medicines 6.5.5.1. African trypanosomiasis 6.5.5.1.1. Medicines for the treatment of 1st stage African trypanosomiasis
ATC codes: P01CA03
EMLc
Indication
Gambiense trypanosomiasis ICD11 code: 1F51.0
INN
Fexinidazole
Medicine type
Chemical agent
List type
Core (EML)
(EMLc)
Additional notes
For the treatment of 1st and 2nd stage of human African trypanosomiasis due to Trypanosoma brucei gambinense and Trypanosoma brucei rhodesiense infection
Formulations
Oral > Solid: 600 mg
EML status history
First added in 2019 (TRS 1021)
Changed in 2025 (TRS 1064)
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
Fexinidazole
DrugBank
Fexinidazole
Summary of evidence and Expert Committee recommendations
Update to note following recommendation of fexinidazole for the treatment of Trypanosoma brucei rhodesiense infection.