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ATC codes: J01MA01
Indication
Multi-drug resistant Mycobacterium tuberculosis ICD11 code: ML32.00
INN
Ofloxacin
Medicine type
Chemical agent
Antibiotic groups
List type
Complementary
Additional notes
Levofloxacin may be an alternative based on availability and programme considerations.
Formulations
Oral > Solid: 200 mg ; 400 mg
EML status history
First added in 1999 (TRS 895)
Changed in 2007 (TRS 946)
Removed in 2013 (TRS 985)
Sex
All
Age
Adolescents and adults
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
DrugBank
Summary of evidence and Expert Committee recommendations
On the basis of WHO guideline recommendations, public health needs and available evidence on efficacy and safety, the Expert Committee recommended that ofloxacin should be replaced by levofloxacin, with a note to indicate that ofloxacin and moxifloxacin may be used as alternatives in the treatment of MDR-TB.