Export

Imipenem + cilastatin
Not recommended as an essential medicine
Section:
6. Anti-infective medicines 6.2. Antibacterials 6.2.2. Watch group antibiotics
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ATC codes: J01DH51
EMLc
Indication
Pseudomonas aeruginosa resistant to other antibiotic ICD11 code: MG50.8Y
INN
Imipenem + cilastatin
Medicine type
Chemical agent
Antibiotic groups
WATCH
List type
Complementary (EML)
(EMLc)
Formulations
Parenteral > General injections > IV: 250 mg (as monohydrate) + 250 mg (as sodium salt) powder for injection ; 500 mg (as monohydrate) + 500 mg (as sodium salt) powder for injection
EML status history
First added in 1997 (TRS 882)
Changed in 2002 (TRS 914)
Changed in 2007 (TRS 950)
Changed in 2009 (TRS 958)
Removed in 2017 (TRS 1006)
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
Imipenem + cilastatin
DrugBank
Imipenem ,
Cilastatin
Summary of evidence and Expert Committee recommendations
As part of the syndrome-based comprehensive review of antibacterials on the Model Lists, imipenem + cilastatin was removed from the EML and EMLc. However, it is acknowledged in the lists as an alternative to meropenem except for acute bacterial meningitis where meropenem is preferred.