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Melarsoprol
Essential medicine status
Section:
6. Anti-infective medicines 6.5. Antiprotozoal medicines 6.5.5. Antitrypanosomal medicines 6.5.5.1. African trypanosomiasis 6.5.5.1.2. Medicines for the treatment of 2nd stage African trypanosomiasis
ATC codes: P01CD01
EMLc
Indication
Rhodesiense trypanosomiasis ICD11 code: 1F51.1
INN
Melarsoprol
Medicine type
Chemical agent
List type
Core (EML)
Complementary (EMLc)
Formulations
Parenteral > General injections > IV: 3.6% in 5 mL ampoule solution (180 mg of active compound)
EML status history
First added in 1977 (TRS 615)
Changed in 1979 (TRS 641)
Changed in 1987 (TRS 770)
Changed in 2007 (TRS 946)
Changed in 2007 (TRS 950)
Changed in 2009 (TRS 958)
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
Melarsoprol
DrugBank
Melarsoprol
Summary of evidence and Expert Committee recommendations
Melarsoprol was moved to the Complementary List of the EMLc due to safety concerns of its use in children.