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Pyridostigmine
Essential medicine status
Section:
20. Muscle relaxants (peripherally-acting) and cholinesterase inhibitors
ATC codes: N07AA02
EMLc
Indication
Myasthenia gravis ICD11 code: 8C70.Z
INN
Pyridostigmine bromide
Medicine type
Chemical agent
List type
Complementary (EML)
(EMLc)
Formulations
Parenteral > General injections > IV: 5 mg per mL in ampoule or vial (pyridostigmine bromide)
Oral > Solid > tablet: 60 mg scored (pyridostigmine bromide)
EML status history
First added in 1977 (TRS 615)
Changed in 1979 (TRS 641)
Changed in 1993 (TRS 850)
Changed in 2003 (TRS 920)
Changed in 2007 (TRS 950)
Changed in 2025 (TRS 1064)
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
Pyridostigmine
DrugBank
Pyridostigmine
Summary of evidence and Expert Committee recommendations
Following the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended: - the deletion of pyridostigmine injection 1 mg in 1 mL ampoule; - the addition of pyridostigmine injection 5 mg/mL in ampoule or vial - to modify the formulation descriptions to better describe the available dosage forms.