Export

EN
FR
ATC codes: N07BC02
EMLc
Indication
Chronic cancer pain ICD11 code: ML00.10
INN
Methadone
Medicine type
Chemical agent
List type
Complementary (EML)
(EMLc)
Additional notes
For the management of cancer pain
Formulations
Oral > Liquid: 5 mg per 5 mL (methadone hydrochloride) ; 25 mg per 5 mL (methadone hydrochloride) ; 50 mg per 5 mL concentrate for oral liquid (methadone hydrochloride) (EML) ; 10 mg per mL concentrate for oral liquid (methadone hydrochloride) (EML)
Oral > Solid > tablet: 5 mg (methadone hydrochloride) ; 10 mg (methadone hydrochloride) (EML)
EML status history
First added in 2017 (TRS 1006)
Changed in 2025 (TRS 1064)
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
DrugBank
Summary of evidence and Expert Committee recommendations
Following the review of the age-appropriateness of formulations for children on the EMLc, the Expert Committee recommended: - the deletion of methadone tablet 10 mg from the EMLc; - the deletion of methadone oral liquid 10 mg/5 mL from the EMLc; - the deletion of methadone concentrate for oral liquid 10 mg/mL from the EMLc - to modify the formulation descriptions of methadone concentrate for oral liquid to better describe the available dosage forms.