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Sodium thiosulfate
Essential medicine status
Section:
4. Antidotes and other substances used in poisonings 4.2. Antidotes and other substances used in poisonings > Specific
ATC codes: V03AB06
Indication
Harmful effects of or exposure to noxious substances, chiefly nonmedicinal as to source, not elsewhere classified ICD11 code: NE61
Medicine type
Chemical agent
List type
Core
Formulations
Parenteral > General injections > IV: 250 mg per mL in 50 mL ampoule
EML status history
First added in 1979 (TRS 641)
Changed in 2007 (TRS 950)
Sex
All
Age
Adolescents and adults
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
Sodium thiosulfate
DrugBank
Sodium thiosulfate (Thiosulfuric acid)
Summary of evidence and Expert Committee recommendations
The EMLc Subcommittee noted that sodium thiosulfate is licensed for use in cyanide poisoning, but the clinical need in children was not clear. The Subcommittee therefore recommended that the public health relevance of sodium nitrite should be clarified before it is added to the EMLc.