Export

Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed Removed
ATC codes: J01AA12
EMLc
Indication
Other specified bacterial diseases ICD11 code: 1C4Y
INN
Tigecycline
Medicine type
Chemical agent
Antibiotic groups
List type
Complementary (EML)
(EMLc)
Formulations
Parenteral > General injections > IV: 50 mg in vial powder for injection
EML status history
First added in 2017 (TRS 1006)
Removed in 2019 (TRS 1021)
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Wikipedia
DrugBank
Summary of evidence and Expert Committee recommendations
With regard to the EML listing of antibiotics, the Committee endorsed revised criteria for the inclusion of Reserve group antibiotics on the Model List. Namely, Reserve group antibiotics should be included individually on the Model List when they have a favourable benefit-risk profile and proven activity against “Critical Priority” or “High Priority” pathogens as identified by the WHO Priority Pathogens List, most notably carbapenem resistant Enterobacteriaceae. Subsequently, the Committee recommended the removal of aztreonam, fourth- and fifth-generation cephalosporins (as classes), tigecycline and daptomycin from the EML and EMLc as these antibiotics did not meet the revised criteria for inclusion on the Model Lists as individual Reserve group agents.