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Azathioprine
Essential medicine status
Section:
8. Immunomodulators and antineoplastics 8.1. Immunomodulators for non-malignant disease
ATC codes: L04AX01
EMLc
Indication
Failure or rejection of transplanted organs or tissues ICD11 code: NE84
INN
Azathioprine
Medicine type
Chemical agent
List type
Complementary (EML)
(EMLc)
Formulations
Parenteral > General injections > IV: 100 mg in vial powder for injection (as sodium salt) ; 50 mg in vial powder for injection (as sodium salt) (EMLc)
Oral > Liquid: 10 mg per mL (EMLc)
Oral > Solid > tablet: 50 mg (scored) ; 25 mg (EMLc)
EML status history
First added in 1979 (TRS 641)
Changed in 1984 (TRS 722)
Changed in 2002 (TRS 914)
Changed in 2003 (TRS 920)
Changed in 2007 (TRS 950)
Changed in 2023 (TRS 1049)
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
Azathioprine
DrugBank
Azathioprine
Summary of evidence and Expert Committee recommendations
Following the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended the addition of new formulations of azathioprine (oral liquid 10 mg/mL, powder for injection 50 mg, and tablet 25 mg) to the EMLc.