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Pentamidine
Essential medicine status
Section:
6. Anti-infective medicines 6.5. Antiprotozoal medicines 6.5.5. Antitrypanosomal medicines 6.5.5.1. African trypanosomiasis 6.5.5.1.1. Medicines for the treatment of 1st stage African trypanosomiasis
ATC codes: P01CX01
EMLc
Indication
African trypanosomiasis ICD11 code: 1F51
INN
Pentamidine
Medicine type
Chemical agent
List type
Core (EML)
(EMLc)
Additional notes
To be used for the treatment of Trypanosoma brucei gambiense infection.
Formulations
Parenteral > General injections > IM: 300 mg in vial (as isetionate) powder for injection
EML status history
First added in 1977 (TRS 615)
Changed in 1979 (TRS 641)
Changed in 1987 (TRS 770)
Changed in 1997 (TRS 882)
Changed in 2003 (TRS 920)
Changed in 2007 (TRS 946)
Changed in 2007 (TRS 950)
Changed in 2023 (TRS 1049)
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
Pentamidine
DrugBank
Pentamidine
Summary of evidence and Expert Committee recommendations
Following the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended the deletion of pentamidine 200 mg powder for injection and the addition of pentamidine 300 mg powder for injection to the EML and EMLc.