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Nifurtimox
Essential medicine status
Section:
6. Anti-infective medicines 6.5. Antiprotozoal medicines 6.5.5. Antitrypanosomal medicines 6.5.5.1. African trypanosomiasis 6.5.5.1.2. Medicines for the treatment of 2nd stage African trypanosomiasis
ATC codes: P01CC01
EMLc
Indication
African trypanosomiasis ICD11 code: 1F51
INN
Nifurtimox
Medicine type
Chemical agent
List type
Core (EML)
(EMLc)
Additional notes
Only to be used in combination with eflornithine, for the treatment of Trypanosoma brucei gambiense infection.
Formulations
Oral > Solid > tablet: 30 mg (scored) ; 120 mg (scored)
EML status history
First added in 2009 (TRS 958)
Changed in 2013 (TRS 985)
Changed in 2023 (TRS 1049)
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
Nifurtimox
DrugBank
Nifurtimox
Summary of evidence and Expert Committee recommendations
Following the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended the deletion of nifurtimox 250 mg tablets from the EML and EMLc, and the addition of nifurtimox 30 mg tablets to the EMLc (Section 6.5.5.1).