General description
Atropine is a muscarinic antagonist with multiple therapeutic indications including reduction of salivary and bronchial secretions during surgical procedures, treatment of organophosphate poisoning, and as a cycloplegic and mydriatic agent following topical administration into the eye.
Medicine type
Chemical agent
EML status history
First added in 1977
(TRS
615)
for
Exposure to or harmful effects of undetermined intent of pesticides
Added in 1987
(TRS
770)
for
Parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics
Added in 1989
(TRS
796)
for
Anterior uveitis
Changed in 2021
(TRS
1035)
for
Cycloplegic drug
Therapeutic equivalent for
Wikipedia
DrugBank
Recommendations
Section
Preoperative medication and sedation for short-term procedures
- Parenteral > General injections > unspecified: 1 mg in 1 mL ampoule (atropine sulfate)
Section
Antidotes and other substances used in poisonings > Specific
- Parenteral > General injections > unspecified: 1 mg in 1 mL ampoule (atropine sulfate)
Section
Ophthalmological preparations > Mydriatics
- Local > Ophthalmological > Solution (eye drops): 0.1% (sulfate); 0.5% (sulfate); 1% (sulfate)
Indications