General description
Neostigmine is a reversible anticholinesterase agent indicated as a treatment for myasthenia gravis; and for use in the reversal of non-depolarizing muscle relaxants administered during surgery.
INN
Neostigmine bromide
ATC codes
Medicine type
Chemical agent
EML status history
First added in 1977
(TRS
615)
for
Anticholinesterase reversible
Added in 1977
(TRS
615)
for
Myasthenia gravis
Added in 2025
(TRS
1064)
for
Myasthenia gravis
Wikipedia
DrugBank
Recommendations
Section
Muscle relaxants (peripherally-acting) and cholinesterase inhibitors
- Parenteral > General injections > unspecified: 0.5 mg per mL in 1 mL ampoule (neostigmine metilsulfate); 2.5 mg per mL in 1 mL ampoule (neostigmine metilsulfate)
- Oral > Solid > tablet: 15 mg (neostigmine bromide)
Indications
Section
Medicines for myasthenia gravis
- Parenteral > General injections > unspecified: 0.5 mg per mL in 1 mL ampoule (neostigmine metilsulfate); 2.5 mg per mL in 1 mL ampoule (neostigmine metilsulfate)
- Oral > Solid > tablet: 15 mg (neostigmine bromide)
Indications