Description générale
Calcium folinate (also known as leucovorin, folinic acid) is a folic acid derivative that acts as a modulating and rescue agent in cancer chemotherapy protocols.
INN
Calcium folinate
Codes ATC
Type de médicament
Chemical agent
Historique des statuts LME
Ajouté pour la première fois en 1979
(TRS
641)
pour
Malignant neoplasms of colon
Ajouté en 1979
(TRS
641)
pour
Malignant neoplasm metastasis in large intestine
Ajouté en 1979
(TRS
641)
pour
Malignant trophoblastic neoplasms of placenta
Ajouté en 1979
(TRS
641)
pour
Burkitt lymphoma including Burkitt leukaemia
Ajouté en 1979
(TRS
641)
pour
Osteosarcoma of bone and articular cartilage of unspecified sites
Ajouté en 1979
(TRS
641)
pour
Malignant neoplasms of rectum
Ajouté en 1979
(TRS
641)
pour
Unspecified malignant neoplasms of ill-defined or unspecified sites
Retiré en 2015
(TRS
994)
pour
Unspecified malignant neoplasms of ill-defined or unspecified sites
Wikipédia
DrugBank
Recommandations
Section
Cytotoxic medicines
- Parenteral > General injections > unspecified: 3 mg per mL in 10 mL ampoule; 7.5 mg per mL in 2 mL ampoule; 10 mg per mL in 5 mL ampoule
- Oral > Solid > tablet: 15 mg; 5 mg; 25 mg
- Oral > Solid: 15 mg tablet
- Parenteral > General injections > unspecified: 3 mg per mL in 10 mL ampoule
Indications
Malignant neoplasms of colon
Osteosarcoma of bone and articular cartilage of unspecified sites
Burkitt lymphoma including Burkitt leukaemia
Malignant neoplasm metastasis in large intestine
Malignant neoplasms of rectum
Malignant trophoblastic neoplasms of placenta
Unspecified malignant neoplasms of ill-defined or unspecified sites