General description
Fluorouracil is an antineoplastic anti-metabolite used in treatment protocols for many cancers, including topically for skin cancer.
INN
Fluorouracil
ATC codes
Medicine type
Chemical agent
EML status history
First added in 1977
(TRS
615)
for
Unspecified malignant neoplasms of ill-defined or unspecified sites
Added in 1989
(TRS
796)
for
Plantar warts
Added in 2015
(TRS
994)
for
Malignant neoplasms of breast
Added in 2015
(TRS
994)
for
Malignant neoplasms of colon
Added in 2015
(TRS
994)
for
Malignant neoplasms of nasopharynx
Added in 2015
(TRS
994)
for
Malignant neoplasm metastasis in large intestine
Added in 2015
(TRS
994)
for
Malignant neoplasms of rectum
Removed in 2015
(TRS
994)
for
Unspecified malignant neoplasms of ill-defined or unspecified sites
Wikipedia
DrugBank
Recommendations
Section
Cytotoxic medicines
- Parenteral > General injections > IV: 50 mg per mL in vial
- Parenteral > General injections > IV: 50 mg per mL in 5 mL ampoule
Section
Dermatological medicines > Medicines affecting skin differentiation and proliferation
- Local > Topical > Ointment: 5%
Indications