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Essential medicine status
ATC codes: C03DA01
EMLc
Indication
Ascites ICD11 code: ME04
INN
Spironolactone
Medicine type
Chemical agent
List type
Core (EML)
Complementary (EMLc)
Formulations
Oral > Liquid: 25 mg per 5 mL (EMLc)
Oral > Solid > tablet: 25 mg ; 12.5 mg (EMLc)
EML status history
First added in 1977 (TRS 615)
Removed in 1979 (TRS 641)
Added in 1982 (TRS 685)
Changed in 1987 (TRS 770)
Changed in 1997 (TRS 882)
Changed in 2007 (TRS 950)
Changed in 2009 (TRS 958)
Changed in 2025 (TRS 1064)
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Summary of evidence and Expert Committee recommendations
Following the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended: - the addition of spironolactone 12.5 mg tablets to the EMLc; - the deletion of the 5 mg/5 mL and 10 mg/5mL strengths of spironolactone oral liquid because of unavailability as proprietary products.