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Sulfadoxine + pyrimethamine
Essential medicine status
Section:
6. Anti-infective medicines 6.5. Antiprotozoal medicines 6.5.3. Antimalarial medicines 6.5.3.2. Antimalarial medicines > Medicines for chemoprevention
ATC codes: P01BD51
EMLc
Indication
Malaria ICD11 code: 1F4Z
INN
Sulfadoxine + pyrimethamine
Medicine type
Chemical agent
List type
Core (EML)
(EMLc)
Additional notes
For intermittent preventive treatment of malaria in infants
Formulations
Oral > Solid > dispersible tablet: 250 mg + 12.5 mg tablet (EMLc)
EML status history
First added in 2019 (TRS 1021)
Changed in 2025 (TRS 1064)
Sex
All
Age
Children (1 month - 12 years)
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
Sulfadoxine + pyrimethamine
DrugBank
Sulfadoxine ,
Pyrimethamine
Summary of evidence and Expert Committee recommendations
Following the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended: - to replace the listing for sulfadoxine + pyrimethamine tablets for use in intermittent preventive treatment of malaria in infants with a dispersible tablet formulation of the same strengths.