Protamine sulfate was added to the complementary list of the EMLc to reverse the effect of heparin. The Subcommittee accepted that medicines affecting coagulation were essential for children and endorsed protamine sulfate for inclusion in the EMLc. Because of the need for specialist supervision of the administration of heparin sodium, protamine sulfate and warfarin in children, the Subcommittee recommended that these three medicines be included in the Complementary List.