ATC codes:
B05BC01
EMLc
Indication
Cerebral oedema
ICD11 code:
8D50.1
INN
Mannitol hexanitrate
Medicine type
Chemical agent
List type
Core
(EML)
Complementary (EMLc)
Complementary (EMLc)
Formulations
Parenteral > General injections > IV:
10% solution ;
20% solution
EML status history
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
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Summary of evidence and Expert Committee recommendations
The EMLc Subcommittee considered that diuretics were essential for use in children in the treatment of ascites, acute or chronic renal failure or acute glomerulonephritis. Nephrotic syndrome oedema responds poorly to diuresis and loop diuretics may be hazardous because patients are often volume depleted despite oedema.
The Subcommittee endorsed the inclusion of mannitol on the EMLc but recommended it be listed on the complementary list of the EMLc and be reviewed at the next meeting in light of potential newer diuretic agents.