An application was submitted by the Availability of Quality Maternal Health Products (AQMHP) Working Group, Maternal Health Technical Resources Team, UN Commission on Life Saving Commodities for Women and Children, requesting a revision of the language used to describe magnesium sulfate on the EML. An expert review of the application was prepared by one member of the Expert Committee. No public comments on the application were received. Magnesium sulfate is currently included on the 18th Model List as: Injection: 500 mg/ml in 2-ml ampoule; 500 mg/ml in 10-ml ampoule. The application proposed revising the description of the listed formulations to include additional information as follows: Injection: 0.5 g/ml in 2-ml ampoule (1 g in 2 ml; 50% w/v); 0.5 g/ml in 10-ml ampoule (5 g in 10 ml; 50% w/v). No other changes were requested. The rationale given for the suggested changes was that, in many international and national clinical guidelines, the concentration of magnesium sulfate solutions required for treatment is specified as a percentage. It is claimed that some providers have difficulty understanding how much magnesium sulfate this represents in a specific volume of water and there is concern that this confusion may lead to dosing errors, especially in emergency situations. It was asserted in the application that the proposed additional information in the magnesium sulfate entry in the EML will provide improved clarity and understanding in relation to the contents of magnesium ampoules produced commercially. The Expert Committee noted that dosing schedules in WHO’s Managing complications of pregnancy and childbirth: a guide for midwives and doctors (1) include the recommended dose of magnesium sulfate both in grams (g) and as a percentage strength of magnesium sulfate solution. The Expert Committee also noted that WHO guidelines recommend magnesium sulfate for the prevention of eclampsia in women with severe preeclampsia and for treatment of women with eclampsia, in preference to other anticonvulsants (2). Magnesium sulfate has been included on the EML for use in eclampsia and severe pre-eclampsia since 1995. The Expert Committee considered that the requested amendments to the description of magnesium sulfate on the EML were reasonable and may serve to provide greater clarity for providers. The Committee considered further clarity could be achieved with the addition of the words “equivalent to” and by disambiguation of “w/v” to “weight/volume” and therefore recommended that the listing for magnesium sulfate be amended to read as follows: magnesium sulfate* Injection: 0.5 g/mL in 2-mL ampoule (equivalent to 1 g in 2 mL; 50% weight/volume); 0.5 g/mL in 10 mL ampoule (equivalent to 5 g in 10 mL; 50% weight/volume) * For use in eclampsia and severe pre-eclampsia and not for otherconvulsant disorders. References: 1. Managing complications in pregnancy and childbirth : a guide for midwives and doctors. Geneva: World Health Organization; 2007. 2. WHO recommendations for prevention and treatment of pre-eclampsia and eclampsia. Geneva: World Health Organization; 2011.