ATC codes:
J01DD01
EMLc
Indication
Other specified pneumonia
ICD11 code:
CA40.Y
INN
Cefotaxime
Medicine type
Chemical agent
Antibiotic groups
List type
Core
(EML)
(EMLc)
(EMLc)
Additional notes
3rd generation cephalosporin of choice for use in hospitalized neonates.
Formulations
Parenteral > General injections > unspecified:
250 mg in vial powder for injection (as sodium salt) ;
500 mg in vial powder for injection (as sodium salt) ;
1 g in vial powder for injection (as sodium salt) ;
2 g in vial powder for injection (as sodium salt)
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Read more
about patents.
Wikipedia
DrugBank
Expert Committee recommendation
The Expert Committee recommended the inclusion of a new strength, child-friendly dispersible tablet formulation of amoxicillin + clavulanic acid (200 mg + 28.5 mg) as an Access group antibiotic on the core list of the EMLc for treatment of bacterial infections in children – specifically those infections for which amoxicillin + clavulanic acid is already recommended on the EMLc. The Committee noted that the 7:1 ratio of amoxicillin to clavulanic acid is associated with similar efficacy to the 4:1 ratio but has a reduced frequency of gastrointestinal adverse effects. The Committee endorsed the importance of age-appropriate formulations to better meet the dosing needs of children.
Following the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended:
- the addition of a new formulation of amoxicillin + clavulanic acid (dispersible tablet 250 mg + 62.5 mg) to the EMLc.
- the addition of new strength formulations of cefotaxime (powder for injection: 500 mg; 1 g; 2 g (as sodium) in vial) to the EML and EMLc.
- the addition of a new strength formulation of ceftriaxone (powder for injection: 500 mg (as sodium) in vial) to the EML and EMLc.
EML recommendations: Other specified pneumonia
First choice
Second choice
Hospital-acquired pneumonia
First choice
Second choice