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ATC codes: A01AB17
EMLc
Indication
Intestinal infections due to Clostridioides difficile ICD11 code: 1A04
INN
Metronidazole
Medicine type
Chemical agent
Antibiotic groups
List type
Core (EML)
(EMLc)
Formulations
Oral > Liquid: 200 mg per 5 mL (as benzoate)
Local > Rectal > Suppository: 500 mg suppository (EML) ; 1 g suppository (EML)
Parenteral > General injections > unspecified: 500 mg per 100 mL in vial Injection
Oral > Solid > tablet: 200 mg ; 250 mg ; 400 mg ; 500 mg
EML status history
First added in 2017 (TRS 1006)
Changed in 2023 (TRS 1049)
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Expert Committee recommendation
Following the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended a note be added to the listing of oral vancomycin on the EML and EMLc to indicate that the powder for injection dosage form may also be used for oral administration. Following the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended that the range of strengths of metronidazole tablets be replaced with reference to specific strengths on the EML and EMLc.
EML recommendations: Intestinal infections due to Clostridioides difficile
First choice
Second choice
First choice
Second choice