Export

EN
FR
Methotrexate
Not recommended as an essential medicine
Section:
8. Immunomodulators and antineoplastics 8.2. Antineoplastics and supportive medicines 8.2.1. Cytotoxic medicines
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ATC codes: L01BA01
EMLc
Indication
Unspecified malignant neoplasms of ill-defined or unspecified sites ICD11 code: 2D9Z
INN
Methotrexate
Medicine type
Chemical agent
List type
Complementary (EML)
(EMLc)
Formulations
Parenteral > General injections > IV: 50 mg in vial (as sodium salt)
Oral > Solid: 2.5 mg (as sodium salt)
EML status history
First added in 1977 (TRS 615)
Changed in 1979 (TRS 641)
Changed in 2002 (TRS 914)
Changed in 2007 (TRS 950)
Removed in 2015 (TRS 994)
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
Methotrexate
DrugBank
Methotrexate
Summary of evidence and Expert Committee recommendations
As part of the comprehensive review of cancer medicines undertaken by the Expert Committee in 2015, listing of methotrexate was reviewed and specific indications for its use were recommended. Refer to the 2015 recommendation(s) for methotrexate for more information.