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Model List of Essential Medicines
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Found 38 recommendations for 19 medicines and 1 therapeutic equivalent
Removed medicines and rejected applications are not shown.
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6.2.3. Reserve group antibiotics
Cefiderocol
General information
Section
Reserve group antibiotics
Parenteral > General injections > IV: 1 g in vial (as sulfate tosylate) powder for injection
Indications
Carbapenem-resistant Pseudomonas aeruginosa
Carbapenem resistant Enterobacterales
Ceftazidime + avibactam
General information
Section
Reserve group antibiotics
Parenteral > General injections > IV: 2 g in vial + 0.5 g in vial powder for injection
Indications
Carbapenem-resistant Pseudomonas aeruginosa
Carbapenem resistant Enterobacterales
Ceftolozane + tazobactam
General information
Section
Reserve group antibiotics
Parenteral > General injections > IV: 1 g + 0.5 g powder for injection
Indications
Carbapenem-resistant Pseudomonas aeruginosa
Colistin (injection)
General information
Section
Reserve group antibiotics
Parenteral > General injections > unspecified: 1 million IU in vial (as colistemethate sodium) (equivalent to 34 mg colistin base activity)
Indications
Carbapenem resistant Acinetobacter baumannii
Carbapenem-resistant Pseudomonas aeruginosa
Carbapenem resistant Enterobacterales
Fosfomycin (injection)
General information
Section
Reserve group antibiotics
Parenteral > General injections > IV: 2 g in vial (as sodium) powder for injection; 4 g in vial (as sodium) powder for injection
Indications
Carbapenem resistant Acinetobacter baumannii
Carbapenem-resistant Pseudomonas aeruginosa
Carbapenem resistant Enterobacterales
Linezolid
General information
Section
Reserve group antibiotics
Parenteral > General injections > IV: 2 mg per mL in 300 mL bag
Oral > Liquid: 100 mg per 5 mL powder for oral liquid
Oral > Solid > dispersible tablet: 150 mg
Oral > Solid > tablet: 600 mg
Indications
Methicillin resistant Staphylococcus aureus
Vancomycin resistant Staphylococcus aureus
Vancomycin resistant Enterococcus
Meropenem + vaborbactam
General information
Section
Reserve group antibiotics
Parenteral > General injections > IV: 1 g in vial + 1 g in vial powder for injection
Indications
Carbapenem-resistant Pseudomonas aeruginosa
Carbapenem resistant Enterobacterales
Carbapenem resistant Acinetobacter baumannii
Plazomicin
General information
Section
Reserve group antibiotics
Parenteral > General injections > IV: 500 mg per 10 mL
Indications
Carbapenem resistant Acinetobacter baumannii
Carbapenem-resistant Pseudomonas aeruginosa
Carbapenem resistant Enterobacterales
Polymyxin B (injection)
General information
Section
Reserve group antibiotics
Parenteral > General injections > IV: 500000 IU in vial powder for injection (equivalent to 50 mg polymyxin B base)
Indications
Carbapenem resistant Acinetobacter baumannii
Carbapenem-resistant Pseudomonas aeruginosa
Carbapenem resistant Enterobacterales
Tedizolid
General information
Section
Reserve group antibiotics
Indications
Therapeutic equivalent to
linezolid
for
Methicillin resistant Staphylococcus aureus
Therapeutic equivalent to
linezolid
for
Vancomycin resistant Staphylococcus aureus
Therapeutic equivalent to
linezolid
for
Vancomycin resistant Enterococcus