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Methadone
Essential medicine status
General description
Methadone is a synthetic opioid used to treat chronic pain (adults and children), and in opioid replacement therapy for opioid addiction (adults).
INN
Methadone
Medicine type
Chemical agent
EML status history
First added in 2005 (TRS 933) for Opioid dependence
Added in 2017 (TRS 1006) for Chronic cancer pain
Therapeutic equivalent for
Wikipedia
DrugBank
Recommendations
Section
Medicines for disorders due to psychoactive substance use
  • Oral > Liquid: 5 mg per 5 mL (methadone hydrochloride); 10 mg per 5 mL (methadone hydrochloride); 5 mg per mL concentrate for oral liquid (methadone hydrochloride); 10 mg per mL concentrate for oral liquid (methadone hydrochloride)
Section
Opioid analgesics
  • Oral > Liquid: 5 mg per 5 mL (as hydrochloride); 10 mg per 5 mL (as hydrochloride); 5 mg per mL concentrate for oral liquid (as hydrochloride); 10 mg per mL concentrate for oral liquid (as hydrochloride)
  • Oral > Solid: 5 mg (as hydrochloride); 10 mg (as hydrochloride)