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Dexamethasone
Statut de médicament essentiel
Description générale
Dexamethasone is a corticosteroid used in the treatment of various conditions where corticosteroids are indicated, including pain and oedema due to malignancy, nausea and vomiting, and in treatment protocols for some blood tissue cancers.
INN
Dexamethasone
Codes ATC
H02AB02 C05AA09 L01AA01
Type de médicament
Chemical agent
Historique des statuts LME
Ajouté pour la première fois en 1977 (TRS 615) pour Lymphoid leukaemia, not elsewhere classified
Ajouté en 1991 (TRS 825) pour Palliative care
Ajouté en 2009 (TRS 958) pour Nausea or vomiting
Ajouté en 2019 (TRS 1021) pour Plasma cell myeloma
Wikipédia
Dexamethasone
DrugBank
Dexamethasone
Recommandations
Section
Hormones and antihormones
  • Oral > Liquid: 2 mg per 5 mL (as sodium phosphate)
  • Parenteral > General injections > unspecified: 4 mg per mL in 1 mL ampoule dexamethasone phosphate (as sodium phosphate, equivalent to 3.3 mg/mL dexamethasone base)
  • Oral > Solid > tablet: 2 mg (as dexamethasone base); 4 mg (as dexamethasone base)
  • Parenteral > General injections > unspecified: 4 mg per mL in 1 mL ampoule dexamethasone phosphate (as sodium phosphate, equivalent to 3.3 mg/mL dexamethasone base
  • Oral > Solid > tablet: 4 mg (as dexamethasone base)
  • Oral > Liquid: 2 mg per 5 mL
  • Oral > Solid: 2 mg; 4 mg
  • Parenteral > General injections > unspecified: 4 mg per mL in 1 mL ampoule (as disodium phosophate salt)
Indications
Lymphoid leukaemia, not elsewhere classified Plasma cell myeloma Burkitt lymphoma including Burkitt leukaemia Anaplastic large cell lymphoma, ALK-positive Anaplastic large cell lymphoma, ALK-negative
Section
Antiallergics and medicines used in anaphylaxis
  • Oral > Liquid: 0.5 mg per 5 mL (as sodium phosphate); 2 mg per 5 mL (as sodium phosphate)
  • Parenteral > General injections > unspecified: 4 mg per mL in 1 mL ampoule dexamethasone phosphate (as sodium phosphate, equivalent to 3.3 mg/mL dexamethasone base)
  • Oral > Solid > tablet: 0.5 mg (as dexamethasone base); 0.75 mg (as dexamethasone base); 1.5 mg (as dexamethasone base); 2 mg (as dexamethasone base); 4 mg (as dexamethasone base)
Indications
Allergic or hypersensitivity conditions of unspecified type
Section
Antiemetic medicines
  • Oral > Liquid: 0.5 mg per 5 mL (as sodium phosphate); 2 mg per 5 mL (as sodium phosphate)
  • Parenteral > General injections > unspecified: 4 mg per mL in 1 mL ampoule dexamethasone phosphate (as sodium phosphate, equivalent to 3.3 mg/mL dexamethasone base)
  • Oral > Solid > tablet: 0.5 mg (as dexamethasone base); 0.75 mg (as dexamethasone base); 1.5 mg (as dexamethasone base); 4 mg (as dexamethasone base); 2 mg (as dexamethasone base)
Indications
Nausea or vomiting
Section
Other medicines administered to the mother
  • Parenteral > General injections > unspecified: 4 mg per mL (dexamethasone phosphate (as sodium))
Indications
Respiratory distress syndrome of the newborn, altered by maternal corticosteroid therapy
Section
Medicines for other common symptoms in palliative care
  • Oral > Liquid: 2 mg per 5 mL (as sodium phosphate); 0.5 mg per 5 mL (as sodium phosphate)
  • Parenteral > General injections > unspecified: 4 mg per mL in 1 mL ampoule (dexamethasone phosphate (as sodium phosphate) equialent to 3.3 mg dexamethasone base)
  • Oral > Solid > tablet: 2 mg (as dexamethasone base); 4 mg (as dexamethasone base); 0.5 mg (as dexamethasone base); 0.75 mg (as dexamethasone base); 1.5 mg (as dexamethasone base)
Indications
Palliative care