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Ondansetron
Essential medicine status
General description
Ondansetron is a selective serotonin 5-HT3 antagonist used in the prevention and treatment of nausea and vomiting.
INN
Ondansetron
Medicine type
Chemical agent
EML status history
First added in 2009 (TRS 958) for Nausea or vomiting
Added in 2011 (TRS 965) for Palliative care
Therapeutic equivalent for
Wikipedia
DrugBank
Recommendations
Section
Medicines for other common symptoms in palliative care
  • Parenteral > General injections > IV: 2 mg per mL in 2 mL ampoule (ondansetron base, as hydrochloride)
  • Oral > Liquid: 4 mg per 5 mL (ondansetron base)
  • Oral > Solid: 4 mg (ondansetron base); 8 mg (ondansetron base)
Indications
Section
Antiemetic medicines
  • Parenteral > General injections > IV: 2 mg per mL in 2 mL ampoule (ondansetron base, as hydrochloride)
  • Oral > Liquid: 4 mg per 5 mL (ondansetron base)
  • Oral > Solid: 4 mg (ondansetron base); 8 mg (ondansetron base); 24 mg (ondansetron base)