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Metronidazole
Essential medicine status
General description

INN
Metronidazole
ATC codes
A01AB17 P01AB01 J01XD01
Medicine type
Chemical agent
Antibiotic groups
ACCESS
EML status history
First added in 1977 (TRS 615) for Amoebiasis
Added in 2017 (TRS 1006) for Peritoneal abscess
Added in 2017 (TRS 1006) for Peritonitis
Added in 2017 (TRS 1006) for Trichomoniasis
Added in 2021 (TRS 1035) for Necrotising fasciitis
Wikipedia
Metronidazole
DrugBank
Metronidazole
Recommendations
Section
Access group antibiotics
  • Oral > Liquid: 200 mg per 5 mL (as benzoate)
  • Oral > Solid: 200 to 500 mg tablet
  • Parenteral > General injections > unspecified: 500 mg per 100 mL in vial Injection
  • Local > Rectal > Suppository: 500 mg suppository; 1 g suppository
  • Oral > Solid > tablet: 200 mg; 250 mg; 400 mg; 500 mg
  • Local > Rectal > Suppository: 1 g suppository; 500 mg suppository
Indications
First choice
Intestinal infections due to Clostridioides difficile Trichomoniasis co-prescribed with cefazolin Other specified prophylactic measures co-prescribed with cefotaxime Peritonitis (mild-moderate) co-prescribed with cefotaxime Peritoneal abscess (severe) co-prescribed with cefotaxime Peritoneal abscess (mild-moderate) co-prescribed with cefotaxime Peritonitis (severe) co-prescribed with ceftriaxone Necrotising fasciitis co-prescribed with ceftriaxone Peritonitis (mild-moderate) co-prescribed with ceftriaxone Peritonitis (severe) co-prescribed with ceftriaxone Peritoneal abscess (mild-moderate) co-prescribed with ceftriaxone Peritoneal abscess (severe)
Second choice
co-prescribed with ciprofloxacin Peritoneal abscess (mild-moderate) co-prescribed with ciprofloxacin Peritonitis (mild-moderate)
Other indications
Bacterial infection of unspecified site
Section
Antiamoebic and antigiardiasis medicines
  • Oral > Liquid: 200 mg per 5 mL (as benzoate)
  • Parenteral > General injections > unspecified: 500 mg in 100 mL vial
  • Oral > Solid > tablet: 200 mg; 250 mg; 400 mg; 500 mg
Indications
Amoebiasis