eEML - Electronic Essential Medicines List

General description

Doxorubicin is an anthracycline antineoplastic agent, used in treatment protocols for various cancers.

INN

Doxorubicin

ATC codes

L01DB01 L01AA01

Medicine type

Chemical agent

EML status history

First added in 1977 (TRS 615) for Unspecified malignant neoplasms of unspecified sites

Changed in 2011 (TRS 965) for Lymphoid leukaemia, not elsewhere classified

Changed in 2011 (TRS 965) for Burkitt lymphoma including Burkitt leukaemia

Changed in 2015 (TRS 994) for Malignant neoplasms of breast

Changed in 2015 (TRS 994) for Follicular lymphoma

Changed in 2015 (TRS 994) for Kaposi sarcoma of unspecified primary site

Changed in 2015 (TRS 994) for Hodgkin lymphoma

Changed in 2015 (TRS 994) for Diffuse large B-cell lymphoma, not otherwise specified

Changed in 2015 (TRS 994) for Malignant neoplasms of kidney, except renal pelvis

Removed in 2015 (TRS 994) for Unspecified malignant neoplasms of unspecified sites

Added in 2015 (TRS 994) for Other specified malignant neoplasms of breast

Changed in 2019 (TRS 1021) for Plasma cell myeloma

Application rejected in 2021 (TRS 1035) for Rhabdomyosarcoma primary site

Added in 2023 (TRS 1049) for Anaplastic large cell lymphoma, ALK-positive

Changed in 2023 (TRS 1049) for Anaplastic large cell lymphoma, ALK-negative

Wikipedia

DrugBank

Recommendations

Parenteral > General injections > IV: 10 mg in vial (hydrochloride) powder for injection; 50 mg in vial (hydrochloride) powder for injection; 2 mg per mL in 5 mL vial (hydrochloride); 2 mg per mL in 25 mL vial (hydrochloride)
Parenteral > General injections > IV: 2 mg per mL in 25 mL vial (hydrochloride); 10 mg in vial (hydrochloride) powder for injection; 50 mg in vial (hydrochloride) powder for injection; 2 mg per mL in 5 mL vial (hydrochloride)
Parenteral > General injections > IV: 50 mg in vial (hydrochloride); 10 mg in vial (hydrochloride)
Parenteral > General injections > IV: 2 mg per mL in 25 mL vial (hydrochloride); 2 mg per mL in 5 mL vial (hydrochloride); 10 mg in vial (hydrochloride) powder for injection; 50 mg in vial (hydrochloride) powder for injection
Parenteral > General injections > IV: 10 mg in vial (hydrochloride); 50 mg in vial (hydrochloride)
Parenteral > General injections > IV: 50 mg in vial (hydrochloride) powder for injection; 10 mg in vial (hydrochloride) powder for injection; 2 mg per mL in 5 mL vial (hydrochloride); 2 mg per mL in 25 mL vial (hydrochloride)

Indications

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