eEML - Electronic Essential Medicines List

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Etoposide

Essential medicine status

General description

Etoposide is a plant alkaloid antineoplastic agent, used in treatment protocols for several types of cancer.

INN

Etoposide

ATC codes

Medicine type

Chemical agent

EML status history

First added in 1984 (TRS 722) for Unspecified malignant neoplasms of ill-defined or unspecified sites

Added in 2015 (TRS 994) for Germ cell tumour of testis

Added in 2015 (TRS 994) for Retinoblastoma

Added in 2015 (TRS 994) for Other specified malignant neoplasms of the ovary

Added in 2015 (TRS 994) for Other specified malignant neoplasms of bronchus or lung

Added in 2015 (TRS 994) for Ewing sarcoma of bone and articular cartilage of unspecified sites

Added in 2015 (TRS 994) for Hodgkin lymphoma

Added in 2015 (TRS 994) for Malignant trophoblastic neoplasms of placenta

Added in 2015 (TRS 994) for Burkitt lymphoma including Burkitt leukaemia

Added in 2015 (TRS 994) for Lymphoid leukaemia, not elsewhere classified

Removed in 2015 (TRS 994) for Unspecified malignant neoplasms of ill-defined or unspecified sites

Added in 2021 (TRS 1035) for Myeloid leukaemia

Added in 2021 (TRS 1035) for Malignant neoplasms of kidney, except renal pelvis

Added in 2021 (TRS 1035) for Osteosarcoma of bone and articular cartilage of unspecified sites

Added in 2023 (TRS 1049) for Anaplastic large cell lymphoma, ALK-positive

Added in 2023 (TRS 1049) for Anaplastic large cell lymphoma, ALK-negative

Wikipedia

DrugBank

Recommendations

Parenteral > General injections > IV: 20 mg per mL in 5 mL ampoule
Oral > Solid: 100 mg capsule
Parenteral > General injections > IV: 20 mg per mL in 5 mL ampoule; 100 mg in vial powder for injection (as phosphate)
Oral > Solid: 100 mg capsule; 50 mg capsule

Indications

Unspecified malignant neoplasms of ill-defined or unspecified sites Germ cell tumour of testis Malignant trophoblastic neoplasms of placenta Hodgkin lymphoma Other specified malignant neoplasms of bronchus or lung Other specified malignant neoplasms of the ovary Retinoblastoma Ewing sarcoma of bone and articular cartilage of unspecified sites Lymphoid leukaemia, not elsewhere classified Burkitt lymphoma including Burkitt leukaemia Myeloid leukaemia Malignant neoplasms of kidney, except renal pelvis Osteosarcoma of bone and articular cartilage of unspecified sites Anaplastic large cell lymphoma, ALK-positive Anaplastic large cell lymphoma, ALK-negative