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Etoposide
Essential medicine status
General description
Etoposide is a plant alkaloid antineoplastic agent, used in treatment protocols for several types of cancer.
INN
Etoposide
ATC codes
L01CB01
Medicine type
Chemical agent
EML status history
Changed in 2015 (TRS 994) for Hodgkin lymphoma
Changed in 2015 (TRS 994) for Retinoblastoma
Added in 2021 (TRS 1035) for Myeloid leukaemia
Wikipedia
Etoposide
DrugBank
Etoposide
Recommendations
Section
Cytotoxic medicines
  • Parenteral > General injections > IV: 20 mg per mL in 5 mL ampoule
  • Oral > Solid: 100 mg capsule
  • Parenteral > General injections > IV: 20 mg per mL in 5 mL ampoule; 100 mg in vial powder for injection (as phosphate)
  • Oral > Solid: 100 mg capsule; 50 mg capsule
  • Parenteral > General injections > IV: 100 mg in vial powder for injection (as phosphate); 20 mg per mL in 5 mL ampoule
  • Oral > Solid: 50 mg capsule; 100 mg capsule
Indications
Unspecified malignant neoplasms of unspecified sites Germ cell tumour of testis Malignant trophoblastic neoplasms of placenta Hodgkin lymphoma Other specified malignant neoplasms of bronchus or lung Other specified malignant neoplasms of the ovary Retinoblastoma Ewing sarcoma of bone or articular cartilage of unspecified sites Lymphoid leukaemia, not elsewhere classified Burkitt lymphoma including Burkitt leukaemia Myeloid leukaemia Malignant neoplasms of kidney, except renal pelvis Osteosarcoma of bone or articular cartilage of unspecified sites Anaplastic large cell lymphoma, ALK-positive Anaplastic large cell lymphoma, ALK-negative