General description
Ifosfamide is a nitrogen mustard alkylating agent used in treatment protocols for bone and soft tissue sarcomas, and testicular and ovarian cancers.
INN
Ifosfamide
Medicine type
Chemical agent
EML status history
First added in 2009
(TRS
958)
for
Rhabdomyosarcoma primary site
Added in 2009
(TRS
958)
for
Germ cell tumour of testis
Added in 2009
(TRS
958)
for
Ewing sarcoma of bone and articular cartilage of unspecified sites
Added in 2009
(TRS
958)
for
Osteosarcoma of bone and articular cartilage of unspecified sites
Added in 2009
(TRS
958)
for
Other specified malignant neoplasms of the ovary
Added in 2009
(TRS
958)
for
Unspecified malignant neoplasms of ill-defined or unspecified sites
Removed in 2015
(TRS
994)
for
Unspecified malignant neoplasms of ill-defined or unspecified sites
Therapeutic equivalent for
Wikipedia
DrugBank
Recommendations
Section
Cytotoxic medicines
- Parenteral > General injections > IV: 500 mg in vial powder for injection; 1 g in vial powder for injection; 2 g in vial powder for injection
- Parenteral > General injections > IV: 1 g in vial powder for injection; 2 g in vial powder for injection
Indications
Osteosarcoma of bone and articular cartilage of unspecified sites
Other specified malignant neoplasms of the ovary
Germ cell tumour of testis
Rhabdomyosarcoma primary site
Ewing sarcoma of bone and articular cartilage of unspecified sites
Unspecified malignant neoplasms of ill-defined or unspecified sites