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ATC codes: A10BA02
EMLc
Indication
Type 2 diabetes mellitus ICD11 code: 5A11
INN
Metformin
Medicine type
Chemical agent
List type
Core (EML)
Complementary (EMLc)
Formulations
Oral > Solid: 500 mg (hydrochloride)
EML status history
First added in 1997 (TRS 882)
Changed in 2007 (TRS 950)
Sex
All
Age
Also recommended for children
Therapeutic equivalence
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
DrugBank
Summary of evidence and Expert Committee recommendations
The EMLc Subcommittee noted that there is an emerging need for oral anti diabetic drugs suitable for children due to the increasing obesity epidemic and increasing Type II diabetes in children. The Subcommittee noted that glibenclamide and metformin were still primarily used in adult populations for Type II diabetes. The potential need of these medicines in adolescents and children was recognized. The Subcommittee decided not to include glibenclamide in the EMLc at present. The Subcommittee decided to include metformin in the EMLc on the complementary list. This area should be reviewed at a subsequent meeting taking into account available medicines and the changing epidemiology of Type II diabetes in children under 12 years.