ATC codes: N07BA01
Nicotine dependence ICD11 code: 6C4A.2Z
Medicine type
Chemical agent
List type
Oral > Other: 2 mg chewing gum ; 4 mg chewing gum ; 2 mg lozenge ; 4 mg lozenge ; 1 mg per actuation oral spray
Local > Topical > Transdermal patch: 5 to 30 mg per 16 hour ; 7 to 21 mg per 24 hour
EML status history
First added in 2009 (TRS 958)
Changed in 2023 (TRS 1049)
Adolescents and adults
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Summary of evidence and Expert Committee recommendations
The Expert Committee recommended the inclusion of nicotine lozenges and mouth spray on the core list of the EML as additional forms of nicotine replacement therapy for tobacco and smoking cessation. The Committee noted high-quality evidence from multiple randomized controlled trials that all licensed forms of nicotine replacement therapy are effective at increasing increase cessation rates. The Committee considered that the availability of different forms of nicotine replacement therapy would provide options and choice for patients and clinicians, and could facilitate increased market competition, reduce costs and improve affordable access for national health systems.