The Expert Committee recommended the inclusion of pegfilgrastim (including quality-assured biosimilars) on the complementary list of the EML and EMLc for primary prophylaxis in patients at high risk for developing febrile neutropenia associated with myelotoxic chemotherapy, and for secondary prophylaxis in patients who have experienced neutropenia following prior myelotoxic chemotherapy. The Committee noted that a single dose of pegfilgrastim (once every two weeks) is an efficacious and safe alternative to daily injections of filgrastim. The Committee considered that pegfilgrastim may offer advantages over filgrastim in settings where refrigerated storage outside of secondary treatment centers is limited. In these settings, patients being treated with filgrastim face longer hospital stays or daily clinic visits and this has been associated with lower adherence to treatment and increased risk of life-threatening infections. The Committee noted that filgrastim remains a relevant treatment option for patients in whom a treatment duration of less than 2 weeks is indicated.