Export

ATC codes: N06AB03
Indication
Panic disorder ICD11 code: 6B01
INN
Fluoxetine
Medicine type
Chemical agent
List type
Core
Formulations
Oral > Solid: 20 mg (as hydrochloride)
EML status history
First added in 2023 (TRS 1049)
Sex
All
Age
Adolescents and adults
Therapeutic alternatives
citalopram (ATC codes: N06AB04)
escitalopram (ATC codes: N06AB10)
fluvoxamine (ATC codes: N06AB08)
paroxetine (ATC codes: N06AB05)
sertraline (ATC codes: N06AB06)
Patent information
Patents have expired in most jurisdictions
Wikipedia
DrugBank
Summary of evidence and Expert Committee recommendations
The Expert Committee recommended the inclusion of fluoxetine on the EML for the new indications of use in generalized anxiety disorder, panic disorder, and social anxiety disorder. Listing is recommended with a square box specifying citalopram, escitalopram, fluvoxamine, paroxetine, and sertraline as therapeutic alternatives. The Committee considered that the evidence presented in the application supported the use of fluoxetine and the proposed alternative selective serotonin reuptake inhibitors (SSRIs) for these indications as they were shown to be more effective than placebo in reducing anxiety symptoms and have a well-known and acceptable safety profile.