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Essential medicine status
ATC codes: C03AA03
EMLc
Indication
Oedema ICD11 code: MG29.Z
INN
Hydrochlorothiazide
Medicine type
Chemical agent
List type
Core (EML)
Complementary (EMLc)
Formulations
Oral > Solid: 25 mg
EML status history
First added in 1977 (TRS 615)
Changed in 1979 (TRS 641)
Changed in 1987 (TRS 770)
Changed in 2003 (TRS 920)
Changed in 2007 (TRS 950)
Changed in 2021
Sex
All
Age
Also recommended for children
Therapeutic alternatives
Medicines within the same pharmacological class can be used
Therapeutic alternatives limitations
Therapeutic alternatives are chlorothiazide, chlortalidone and indapamide
Therapeutic alternatives limitations for EMLc
Therapeutic alternatives are chlorothiazide and chlortalidone
Patent information
Patents have expired in most jurisdictions
Summary of evidence and Expert Committee recommendations
Following the review of square box listings on the EML and EMLc, the Expert Committee recommended chlorothiazide, chlortalidone and indapamide be specified as therapeutic alternatives under the square box listing for hydrochlorothiazide on the EML; and chlorothiazide and chlortalidone and indapamide be specified as therapeutic alternatives under the square box listing for hydrochlorothiazide on the EMLc for this indication.