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Essential medicine status
ATC codes: C03AA03
EMLc
Indication
Oedema ICD11 code: MG29.Z
INN
Hydrochlorothiazide
Medicine type
Chemical agent
List type
Core (EML)
Complementary (EMLc)
Formulations
Oral > Solid: 25 mg
EML status history
First added in 1977 (TRS 615)
Changed in 1979 (TRS 641)
Changed in 1987 (TRS 770)
Changed in 2003 (TRS 920)
Changed in 2007 (TRS 950)
Sex
All
Age
Also recommended for children
Therapeutic equivalence
Medicines within the same pharmacological class can be used
Patent information
Patents have expired in most jurisdictions
Summary of evidence and Expert Committee recommendations
The EMLc Subcommittee considered that diuretics were essential for use in children for the treatment of ascites, acute or chronic renal failure or acute glomerulonephritis. Nephrotic syndrome oedema responds poorly to diuresis and loop diuretics may be hazardous because patients are often volume depleted despite oedema. The Subcommittee recommended that hydrochlorothiazide be included on the EMLc in the diuretics section, but should be listed in the complementary list.