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Cyclophosphamide
Essential medicine status
Section:
8. Immunomodulators and antineoplastics 8.2. Antineoplastics and supportive medicines 8.2.1. Cytotoxic medicines
ATC codes: L01AA01
EMLc
Indication
Rhabdomyosarcoma primary site ICD11 code: 2C25.Z
INN
Cyclophosphamide
Medicine type
Chemical agent
List type
Complementary
Formulations
Parenteral > General injections > IV: 500 mg in vial powder for injection ; 1 g in vial powder for injection ; 2 g in vial powder for injection
Oral > Solid: 25 mg tablet ; 50 mg tablet
EML status history
First added in 1977 (TRS 615)
Changed in 2015 (TRS 994)
Changed in 2019 (TRS 1021)
Changed in 2021 (TRS 1035)
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Tags
Wikipedia
Cyclophosphamide
DrugBank
Cyclophosphamide
Summary of evidence and Expert Committee recommendations
The Expert Committee recommended the addition of new strength formulations of cyclophosphamide powder for injection (1 g and 2 g) to the EML and EMLc.
Expert Committee report