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Sofosbuvir
Essential medicine status
Section:
6. Anti-infective medicines 6.4. Antiviral medicines 6.4.4. Antihepatitis medicines 6.4.4.2. Medicines for hepatitis C 6.4.4.2.1. Medicines for hepatitis C > Pangenotypic direct-acting antiviral combinations
ATC codes: J05AP08
Indication
Chronic hepatitis C ICD11 code: 1E91.1
INN
Sofosbuvir
Medicine type
Chemical agent
List type
Core pangenotypic when used in combintaion with daclatasvir.
Formulations
Oral > Solid: 400 mg tablet
EML status history
First added in 2015 (TRS 994)
Changed in 2019 (TRS 1021)
Sex
All
Age
Adolescents and adults
Therapeutic equivalence
daclatasvir (ATC codes: J05AP07)
glecaprevir + pibrentasvir (ATC codes: J05AP57)
sofosbuvir + velpatasvir (ATC codes: J05AP55)
Patent information
Main patent is active in several jurisdictions. For more information on specific patents and license status for developing countries visit www.MedsPal.org
Wikipedia
Sofosbuvir
DrugBank
Sofosbuvir
Summary of evidence and Expert Committee recommendations
The listing for sofosbuvir was qualified by a note indicating that it is pangenotypic when used in combination with daclatasvir. Pangenotypic direct acting antivirals are considered therapeutically equivalent for the purposes of selection and procurement at national level.