ATC codes:
N05BA01
EMLc
Indication
Status epilepticus
ICD11 code:
8A66
INN
Diazepam
Medicine type
Chemical agent
List type
Core
Formulations
Local > Rectal > Gel:
5 mg per mL in 0.5 mL tubes ;
5 mg per mL in 2 mL tubes ;
5 mg per mL in 4 mL tubes
Local > Rectal > Solution: 5 mg per mL in 0.5 mL tubes ; 5 mg per mL in 2 mL tubes ; 5 mg per mL in 4 mL tubes
Local > Rectal > Solution: 5 mg per mL in 0.5 mL tubes ; 5 mg per mL in 2 mL tubes ; 5 mg per mL in 4 mL tubes
EML status history
Sex
All
Age
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
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Summary of evidence and Expert Committee recommendations
In consideration of an application proposing the addition of lorazepam and midazolam for the treatment of repetitive and prolonged convulsive seizures (including status epilpeticus), the Expert Committee recommended the inclusion of parenteral lorazepam with a square box to replace diazepam on the Model List based on its comparative effectiveness and safety with respect to other medicines for the management of prolonged convulsive seizures and status epilepticus in adults and children. The rectal formulation of diazepam was maintained because if is a commercially available preparation and offers an option for treatment of severe seizures in patients when intravenous access is not available.