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ATC codes: J04AB02
EMLc
Indication
Tuberculosis ICD11 code: 1B4Z
INN
Rifampicin
Medicine type
Chemical agent
List type
Core
Formulations
Oral > Liquid: 20 mg per mL (EMLc)
Oral > Solid: 150 mg ; 300 mg
EML status history
First added in 1977 (TRS 615)
Changed in 1979 (TRS 641)
Changed in 2007 (TRS 950)
Sex
All
Age
Also recommended for children
Therapeutic equivalence
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
DrugBank
Summary of evidence and Expert Committee recommendations
There are no international data publicly available that describe the prevalence and incidence of TB in children under 15 years of age, and few clinical trials of treatment on children. However, TB is accepted as a public health priority and therefore treatment of it fulfils the criteria for essential medicines. All four medicines used in standard treatment of tuberculosis (ethambutol, isoniazid, pyrazinamide and rifampicin) are licensed for use in children. The EMLc Subcommittee endorsed all four for inclusion on the EMLc and noted that an oral liquid form of all of them was available. The Subcommittee recommended that all of these single agents be added to the List (ethambutol 25 mg/ml, isoniazid 50 mg/5 ml, pyrazinamide 30 mg/ml, rifampicin 20 mg/ml).