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ATC codes: P01CX02
EMLc
Indication
African trypanosomiasis ICD11 code: 1F51
INN
Suramin sodium
Medicine type
Chemical agent
List type
Core To be used for the treatment of the initial phase of Trypanosoma brucei rhodesiense infection.
Formulations
Parenteral > General injections > IV: 1 g in vial
EML status history
First added in 1977 (TRS 615)
Changed in 1979 (TRS 641)
Changed in 2007 (TRS 946)
Changed in 2007 (TRS 950)
Sex
All
Age
Also recommended for children
Therapeutic equivalence
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Summary of evidence and Expert Committee recommendations
The EMLc Subcommittee recommended that suramin sodium be endorsed for the EMLc for treatment of first-stage of Trypanosoma brucei rhodesiense infections. The Subcommittee noted that African trypanosomiasis is a major public health problem in affected countries. Medicines available for treating this infection are limited. Hence despite the toxicity profile, these medicines are still used. There is a paucity of documented information specific to children and recommendations for adults are usually followed.