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ATC codes: C07AA05
EMLc
Indication
Migraine ICD11 code: 8A80.Z
INN
Propranolol
Medicine type
Chemical agent
List type
Core
Formulations
Oral > Solid: 40 mg tablet (hydrochloride) ; 20 mg tablet (hydrochloride)
EML status history
First added in 1989 (TRS 796)
Changed in 1993 (TRS 850)
Changed in 2007 (TRS 950)
Sex
All
Age
Also recommended for children
Therapeutic equivalence
Medicines within the same pharmacological class can be used
Therapeutic equivalence limitations for EMLc
The square box does not apply to the listing of propranolol on the EMLc.
Patent information
Patents have expired in most jurisdictions
Wikipedia
DrugBank
Summary of evidence and Expert Committee recommendations
The EMLc Subcommittee considered the burden of disease of migraine in children, noting that management is similar to that in adults but fewer drugs are approved for treatment of migraine in children. There is conflicting evidence on the efficacy of propranolol in the prevention of migraine in children, but it is the only medicine approved for the prevention of migraine in children. The Subcommittee therefore recommended that propranolol be endorsed for inclusion in the EMLc but without a square box listing, in the absence of evidence of effectiveness of other beta blocking agents for prevention of migraine in children.