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Cyclophosphamide
Statut de médicament essentiel
Description générale
Cyclophosphamide is an antineoplastic alkylating agent, used in the treatment of many cancers.
INN
Cyclophosphamide
Codes ATC
L01AA01
Type de médicament
Chemical agent
Historique des statuts LME
Ajouté pour la première fois en 1977 (TRS 615) pour Diffuse large B-cell lymphomas
Ajouté en 1977 (TRS 615) pour Follicular lymphoma
Ajouté en 1977 (TRS 615) pour Hodgkin lymphoma
Ajouté en 2019 (TRS 1021) pour Plasma cell myeloma
Wikipédia
Cyclophosphamide
DrugBank
Cyclophosphamide
Recommandations
Section
Cytotoxic medicines
  • Parenteral > General injections > IV: 500 mg in vial powder for injection; 1 g in vial powder for injection; 2 g in vial powder for injection
  • Oral > Solid: 25 mg; 50 mg
  • Oral > Solid: 25 mg tablet
  • Parenteral > General injections > unspecified: 500 mg in vial powder for injection
  • Oral > Solid: 25 mg; 50 mg tablet
Indications
Diffuse large B-cell lymphomas Chronic lymphocytic leukaemia or small lymphocytic lymphoma Malignant neoplasms of breast Malignant trophoblastic neoplasms of placenta Follicular lymphoma Other specified malignant neoplasms of breast Hodgkin lymphoma Rhabdomyosarcoma primary site Ewing sarcoma of bone and articular cartilage of unspecified sites Lymphoid leukaemia, not elsewhere classified Burkitt lymphoma including Burkitt leukaemia Unspecified malignant neoplasms of ill-defined or unspecified sites Plasma cell myeloma Other specified gliomas of brain Malignant neoplasms of kidney, except renal pelvis Anaplastic large cell lymphoma, ALK-positive Anaplastic large cell lymphoma, ALK-negative