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Codes ATC: J01CF02
EMLc
Indication
Sepsis without septic shock Code ICD11: 1G40
INN
Cloxacillin
Type de médicament
Chemical agent
Groupes d'antibiotiques
Type de liste
Liste de base (EML)
(EMLc)
Additional notes
*cloxacillin, dicloxacillin and flucloxacillin are preferred for oral administration due to better bioavailability
Formulations
Oral > Liquid: 125 mg per 5 mL (as sodium salt) powder for oral liquid (EMLc) ; 250 mg per 5 mL (as sodium salt) powder for oral liquid (EMLc)
Parenteral > General injections > unspecified: 500 mg in vial (as sodium salt) powder for injection (EMLc) ; 250 mg in vial (as sodium salt) powder for injection (EMLc)
Oral > Solid > capsule: 500 mg (as sodium salt) (EMLc) ; 1 g (as sodium salt) (EMLc) ; 250 mg (as sodium salt) (EMLc)
Historique des statuts LME
Ajouté pour la première fois en 2017 (TRS 1006)
Modifié en 2021 (TRS 1035)
Modifié en 2023 (TRS 1049)
Sexe
Tous
Âge
Enfants (1 mois - 12 ans)
Équivalence thérapeutique
Des médicaments appartenant à la même classe pharmacologique peuvent être utilisés
Limites de l'équivalence thérapeutique
Therapeutic alternatives are medicines in the 4th level ATC chemical subgroup: J01CF Beta-lactamase resistant penicillins.
Limites d'équivalence thérapeutique pour l'EMLc
Therapeutic alternatives are medicines in the 4th level ATC chemical subgroup: J01CF Beta-lactamase resistant penicillins.
Renseignements sur le brevet
Patents have expired in most jurisdictions
Lire la suite sur les brevets.
Wikipédia
DrugBank
Recommandation du comité d'experts
Following the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended: - the addition of a new strength formulation of amikacin (injection 50 mg/mL (as sulfate) in 2 mL vial) to the EMLc. - the addition of new formulations of amoxicillin (dispersible, scored tablet, 250 mg and 500 mg) to the EMLc. - the addition of new strength formulations of cefotaxime (powder for injection: 500 mg; 1 g; 2 g (as sodium) in vial) to the EML and EMLc. - the addition of a new strength formulation of ceftriaxone (powder for injection: 500 mg (as sodium) in vial) to the EML and EMLc. - the addition of new strength formulations of cloxacillin (capsule 250 mg, powder for injection 250 mg (as sodium) and powder for oral liquid 250 mg/5 mL (as sodium) on the EMLc.
Recommandations de la LME : Sepsis without septic shock
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