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ATC codes: J01CE01
EMLc
Indication
Sepsis without septic shock ICD11 code: 1G40
INN
Benzylpenicillin
Medicine type
Chemical agent
Antibiotic groups
List type
Core (EML)
(EMLc)
Formulations
Parenteral > General injections > unspecified: 600 mg in vial powder for injection (=1 million IU as sodium or potassium salt) (EMLc) ; 3 g in vial powder for injection (=5 million IU as sodium or potassium salt) (EMLc)
EML status history
First added in 2017 (TRS 1006)
Changed in 2023 (TRS 1049)
Sex
All
Age
Children (1 month - 12 years)
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Expert Committee recommendation
Following the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended: - the addition of a new strength formulation of amikacin (injection 50 mg/mL (as sulfate) in 2 mL vial) to the EMLc. - the addition of new formulations of amoxicillin (dispersible, scored tablet, 250 mg and 500 mg) to the EMLc. - the addition of new strength formulations of cefotaxime (powder for injection: 500 mg; 1 g; 2 g (as sodium) in vial) to the EML and EMLc. - the addition of a new strength formulation of ceftriaxone (powder for injection: 500 mg (as sodium) in vial) to the EML and EMLc. - the addition of new strength formulations of cloxacillin (capsule 250 mg, powder for injection 250 mg (as sodium) and powder for oral liquid 250 mg/5 mL (as sodium) on the EMLc.
EML recommendations: Sepsis without septic shock
First choice
Second choice
First choice
Second choice