ATC codes:
J01DD04
EMLc
Indication
Sepsis without septic shock
ICD11 code:
1G40
INN
Ceftriaxone
Medicine type
Chemical agent
Antibiotic groups
List type
Core
(EML)
(EMLc)
(EMLc)
Additional notes
Do not administer with calcium and avoid in infants with hyperbilirubinaemia.
Formulations
Parenteral > General injections > unspecified:
250 mg in vial powder for injection (as sodium salt)
(EMLc)
;
500 mg in vial powder for injection (as sodium salt)
(EMLc)
;
1 g in vial powder for injection (as sodium salt)
(EMLc)
Sex
All
Age
Children (1 month - 12 years)
Age restriction
> 41 weeks corrected gestational age
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Read more
about patents.
Wikipedia
DrugBank
Expert Committee recommendation
In consideration of the review of the age appropriateness of formulations of medicines on the EMLc, and the comparison report of the EML versus EMLc, the Expert Committee recommended changes to the EMLc for addition of new, age-appropriate formulations and strengths of existing essential medicines, deletion of unavailable or age-inappropriate formulations and strengths, and other listing modifications as proposed in the application. The Committee also endorsed the proposals for further review of the public health relevance and evidence for specific medicines for use in children for potential future consideration for inclusion on the EMLc. The Committee noted and welcomed the ongoing review being coordinated by the Secretariat for the remaining sections of the EMLc for consideration by the 2025 Expert Committee.
As a result of the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended:
- the addition of a new strength formulation of amikacin (injection 50 mg/mL (as sulfate) in 2 mL vial) to the EMLc.
- the addition of new formulations of amoxicillin (dispersible, scored tablet, 250 mg and 500 mg) to the EMLc.
- the addition of new strength formulations of cefotaxime (powder for injection: 500 mg; 1 g; 2 g (as sodium) in vial) to the EML and EMLc.
- the addition of a new strength formulation of ceftriaxone (powder for injection: 500 mg (as sodium) in vial) to the EML and EMLc.
- the addition of new strength formulations of cloxacillin (capsule 250 mg, powder for injection 250 mg (as sodium) and powder for oral liquid 250 mg/5 mL (as sodium) on the EMLc.
EML recommendations: Sepsis without septic shock
First choice
Second choice
First choice
gentamicin
co-prescribed with
amoxicillin
gentamicin co-prescribed with ampicillin
gentamicin co-prescribed with benzylpenicillin
gentamicin co-prescribed with ampicillin
gentamicin co-prescribed with benzylpenicillin
Second choice