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ATC codes: J01DD04
EMLc
Indication
Sepsis without septic shock ICD11 code: 1G40
INN
Ceftriaxone
Medicine type
Chemical agent
Antibiotic groups
List type
Core (EML)
(EMLc)
Additional notes
Do not administer with calcium and avoid in infants with hyperbilirubinaemia.
Formulations
Parenteral > General injections > unspecified: 250 mg in vial powder for injection (as sodium salt) (EMLc) ; 1 g in vial powder for injection (as sodium salt) (EMLc) ; 500 mg in vial powder for injection (as sodium salt) (EMLc)
EML status history
First added in 2017 (TRS 1006)
Changed in 2023 (TRS 1049)
Sex
All
Age
Children (1 month - 12 years)
Age restriction
> 41 weeks corrected gestational age
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
DrugBank
Expert Committee recommendation
Following the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended: - the addition of a new strength formulation of amikacin (injection 50 mg/mL (as sulfate) in 2 mL vial) to the EMLc. - the addition of new formulations of amoxicillin (dispersible, scored tablet, 250 mg and 500 mg) to the EMLc. - the addition of new strength formulations of cefotaxime (powder for injection: 500 mg; 1 g; 2 g (as sodium) in vial) to the EML and EMLc. - the addition of a new strength formulation of ceftriaxone (powder for injection: 500 mg (as sodium) in vial) to the EML and EMLc. - the addition of new strength formulations of cloxacillin (capsule 250 mg, powder for injection 250 mg (as sodium) and powder for oral liquid 250 mg/5 mL (as sodium) on the EMLc.
EML recommendations: Sepsis without septic shock
First choice
Second choice
First choice
Second choice